Is Hyaluronic Acid Safe for Pregnancy?

Is Hyaluronic Acid Safe for Pregnancy? Navigating Skincare During Maternity

Pregnancy, a transformative journey of joy and challenges, ushers in a plethora of changes in a woman’s body, and her skin is no exception. As the quest for safe and effective skincare intensifies, a common query arises: “is hyaluronic acid safe for pregnancy?” This article delves deep into the question, can you use hyaluronic acid while pregnant. We also review contrasting it with other popular skincare ingredients, particularly retinol.

Introduction to Hyaluronic Acid

A foundational grasp of what hyaluronic acid is and its role in skincare sets the stage for understanding its safety.

The Hydrating Powerhouse

Hyaluronic acid (HA) is a naturally occurring substance found in our skin, connective tissues, and eyes. Its primary role? Retaining moisture. In fact, it can hold up to 1,000 times its weight in water, making it a hydration hero. It has other benefits as well which we explain here:

Other Benefits of Hyaluronic Acid

Hyaluronic Acid in Skincare

Thanks to its moisture-binding properties, HA is a favored ingredient in many skincare products, from serums to moisturizers. It helps in:

  • Hydration: Enhancing skin’s moisture content.
  • Plumpness: Reducing the appearance of fine lines and wrinkles as you age.
  • Softness: Improving skin texture.

Hyaluronic Acid and Pregnancy

The pivotal question: Is hyaluronic acid safe during pregnancy?

Natural Occurrence Advantage

Given that HA is a substance our bodies produce naturally, topical application in skincare products is generally considered safe1. Most of the hyaluronic acid applied topically remains on the skin’s surface and doesn’t get absorbed into the bloodstream, minimizing risks during pregnancy.

Expert Consensus

Most dermatologists and skincare experts agree that topical hyaluronic acid is safe to use during pregnancy2. As always, though, if you have concerns, consulting your dermatologist or obstetrician is recommended.

Retinol vs. Hyaluronic Acid: A Skincare Showdown

While hyaluronic acid is lauded for hydration, retinol is often celebrated for its anti-aging prowess. But how do they measure up, especially during pregnancy? We also review the question, can you use retinol while breastfeeding, here:

Can You Use Retinol While Breastfeeding?

Retinol: The Age-Defying Maven

Retinol, a derivative of vitamin A, is revered for:

  • Stimulating Collagen Production: Reducing the appearance of fine lines and wrinkles.
  • Enhancing Cell Turnover: Resulting in smoother, more radiant skin.
  • Clearing Acne: By unclogging pores and reducing breakouts.

The Pregnancy Conundrum

Retinol and other vitamin A derivatives are advised against during pregnancy due to potential risks to the fetus3, such as fetal retinoid syndrome. This makes hyaluronic acid a preferred choice for many expectant mothers seeking skincare solutions.

Tips for Skincare During Pregnancy

Navigating skincare during pregnancy can be daunting. Here are some general guidelines:

Simplify Your Routine

Opt for a pared-down routine focusing on hydrating and soothing ingredients like hyaluronic acid.

Patch Test

Hormonal changes, especially during pregnancy, can alter skin sensitivity. Always patch test new products to gauge reactions.

Consult Professionals

Engage with your dermatologist or obstetrician before making significant changes to your skincare regimen or if concerns arise.


Pregnancy is a time of wonder, transformation, and, often, a myriad of questions. When it comes to skincare and the safety of ingredients like hyaluronic acid, the news is good. Hyaluronic acid offers a hydrating solution, especially when compared to ingredients like retinol, which are best avoided during this special time. As always, when in doubt, reaching out to professionals can guide your path to glowing maternal skin.


Disclaimer: This article is intended for informational purposes only and should not be construed as medical advice. Always consult with a qualified healthcare provider for medical advice and treatment.

Hopefully this article was helpful in your skincare journey.  Welcome to Divine Dermatology, PLLC, your beacon for skin care in St. Petersburg, Florida. Under the skilled guidance of Carol Sims-Robertson, MD, our office celebrates all skin types and ages, curating personalized treatments that enhance your natural beauty.

From teens battling acne to adults seeking anti-aging remedies, we offer innovative solutions that cater to every person’s unique needs. At Divine Dermatology, PLLC, we believe in using our expertise so beauty transcends age and skin type. Trust us to transform your skin, elevating your confidence, and revealing the most beautiful you. 

Click here to Schedule your Free Skin Evaluation Today or call us at (727) 528-0321. Embrace the Divine Dermatology difference – where your path to beauty begins.


  1. Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.
  2. Bozzo, P., Chua-Gocheco, A., & Einarson, A. (2011). Safety of skin care products during pregnancy. Canadian Family Physician, 57(6), 665-667.
  3. Basha, M., Wei, W., Bakheet, S. A., Benahmed, F., & Martin, J. (2018). The relevance of vitamin A in breast cancer. Anti-Cancer Agents in Medicinal Chemistry, 18(5), 660-672.